2023年医院高质量共识期刊论文推送(4)

感染科郑明华(共通)在高质量T2(A)期刊Cell Metabolism发表Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans(肝细胞CHRNA4介导免疫细胞产生的乙酰胆碱和吸烟对小鼠和人类MASH的促进作用)；

转化医学实验室李圆凤(共一)在高质量T2(B)期刊Adv Mater发表Two-Tailed Dynamic Covalent Amphiphile Combats Bacterial Biofilms(双尾动态共价两亲体对抗细菌生物膜)；

心血管内科叶浡之(一作)、梁广(通讯)在高质量T2(B)期刊Circ Res发表USP25 Ameliorates Pathological Cardiac Hypertrophy by Stabilizing SERCA2a in Cardiomyocytes(去泛素化酶USP25靶向稳定心肌细胞内SERCA2a改善病理性心肌肥厚)；

联合医学转化中心闫家齐(一作)、张宏博(通讯)在高质量T3(A)期刊Nat Commun发表An autocatalytic multicomponent DNAzyme nanomachine for tumor-specific photothermal therapy sensitization in pancreatic cancer(用于胰腺癌肿瘤特异性光热治疗致敏的自催化多组分DNA酶纳米机)；

转化医学实验室朴银子(一作)、转化医学实验室李圆凤(通讯)在高质量T3(A)期刊Nano Today发表One-component lipidic bicontinuous nanospheres as a smart drug loading platform to eradicate candida bioflim in oral and vaginal infection(构筑仿生类酶活性的纳米药物体系用于清除口腔多菌群生物膜相关感染)；

心血管内科钟凌峰(一作)、叶浡之(通讯)在高质量T3(A)期刊Basic Res Cardiol发表Novel GSDMD inhibitor GI-Y1 protects heart against pyroptosis and ischemia/reperfusion injury by blocking pyroptotic pore formation(新型GSDMD抑制剂GI-Y1通过阻断焦亡孔的形成来保护心脏免受焦亡和缺血/再灌注损伤)；

耳鼻咽喉科李贺(共通)在高质量T3(A)期刊ADV FUNCT MATER发表Recent Advances in Living Algae Seeding Wound Dressing: Focusing on Diabetic Chronic Wound Healing(活藻在糖尿病创面的应用研究进展)；

心血管内科黄祝琦(一作)、梁广(通讯)在高质量T3(B)期刊EMBO Mol Med发表Macrophage DCLK1 promotes atherosclerosis via binding to IKKβ and inducing inflammatory responses(巨噬细胞特异性DCLK1靶向结合IKKβ从而诱导炎症反应促进动脉粥样硬化)；

脊柱外科王宇(一作)、联合医学转化中心邓俊杰(通讯)在高质量T3(B)期刊Small发表Human Adipose Tissue Lysate-Based Hydrogel for Lasting Immunomodulation to Effectively Improve Spinal Cord Injury Repair(人脂肪组织裂解液基水凝胶用于持久的免疫调节从而有效地改善脊髓损伤的修复)；

联合医学转化中心何沁泓(一作)、李花琼(通讯)在高质量T3(B)期刊ADVANCED FUNCTIONAL MATERIALS发表Conductive Hydrogel for Flexible Bioelectronic Device: Current Progress and Future Perspective(用于柔性生物电子器件的导电水凝胶：目前进展和未来展望)；

麻醉科戴锦添(一作)、陈婷(通讯)在高质量T3(B)期刊Eur J Med Chem发表Design, synthesis and biological evaluation of 4-(4-aminophenoxy)picolinamide derivatives as potential antitumor agents(4-(4-氨基苯氧基)吡啶酰胺类抗肿瘤衍生物的设计、合成和生物活性评价)；

联合医学转化中心叶方富(共通)、戴利雄(通讯)在高质量T3(B)期刊J Med Chem发表Rational Design of Gd-DOTA-Type Contrast Agents for Hepatobiliary Magnetic Resonance Imaging(肝胆磁共振成像Gd-DOTA型对比剂的合理设计)；

联合医学转化中心叶方富(共通)、戴利雄(通讯)在高质量T3(B)期刊J Med Chem发表Chiral Gd-DOTA as a Versatile Platform for Hepatobiliary and Tumor Targeting MRI Contrast Agents(手性Gd-DOTA作为肝胆和肿瘤靶向磁共振造影剂的通用平台)；

检验科吴春央(共一)、余方友(通讯)在高质量T3(B)期刊Drug Resist Updat发表Characterization difference of typical KL1, KL2 and ST11-KL64 hypervirulent and carbapenem-resistant Klebsiella pneumoniae(典型KL1、KL2和ST11-KL64型碳青霉烯耐药高毒力肺炎克雷伯菌的差异特征分析)；

感染科郑明华(通讯)在高质量T3(B)期刊Clin Gastroenterol Hepatol发表Metabolically Healthy Obese MAFLD: Are They Truly Healthy?(代谢健康的肥胖 MAFLD:他们真的健康吗?)；

感染科郑明华(通讯)在高质量T3(B)期刊Sci Bull发表The gut microbiome and nicotine metabolism in NAFLD(NAFLD的肠道微生物组和尼古丁代谢)；

胃肠外科沈贤(通讯)在高质量T3(B)期刊Adv Sci发表Engineering Heterogeneous Tumor Models for Biomedical Applications(生物医学应用中的工程异质性肿瘤模型)；

联合医学转化中心张赵文斌(共一)、常江(共通)在高质量T3(B)期刊Bioact Mater发表A biomaterial-based therapy for lower limb ischemia using Sr/Si bioactive hydrogel that inhibits skeletal muscle necrosis and enhances angiogenesis(振荡流激活的骨细胞溶解物基水凝胶调节成骨细胞/破骨细胞内稳态以促进骨修复)；

医学研究中心罗武(共通)在高质量T3(B)期刊Br J Pharmacol发表Discovery of alantolactone as a naturally occurring NLRP3 inhibitor to alleviate NLRP3-driven inflammatory diseases in mice(土木香内酯作为一种天然NLRP3抑制剂，可减轻小鼠NLRP3驱动的炎症性疾病)；

联合医学转化中心邓俊杰(共通)在高质量T3(B)期刊Adv Sci发表Oscillating Fluid Flow Activated Osteocyte Lysate-Based Hydrogel for Regulating Osteoblast/Osteoclast Homeostasis to Enhance Bone Repair(振荡流激活的骨细胞溶解物基水凝胶调节成骨细胞/破骨细胞内稳态以促进骨修复)；

ICU潘景业(共通)在高质量T3(B)期刊Bioact Mater发表Copper ion/gallic acid MOFs-laden adhesive pomelo peel sponge effectively treats biofilm-infected skin wounds and improves healing quality(含铜离子/没食子酸MOFs的柚子皮海绵能有效治疗生物膜感染的皮肤伤口和提高愈合质量)；

ICU潘景业(共通)在高质量T3(B)期刊Adv Sci发表Super-Elastic Carbonized Mushroom Aerogel for Management of Uncontrolled Hemorrhage(超弹性碳化蘑菇气凝胶用于治疗失控的出血)；

检验科周铁丽(共通)在高质量T3(B)期刊Elife发表The evolutionary mechanism of non-carbapenemase carbapenem-resistant phenotypes in Klebsiella spp(克雷伯菌非碳青霉烯酶耐碳青霉烯表型的进化机制)；

省胰腺肝脏危重性病诊治新技术研究重点实验室邓婕(共通)在高质量T3(B)期刊J Control Release发表Supramolecular nanofiber of indomethacin derivative confers highly cyclooxygenase-2 (COX-2) selectivity and boosts anti-inflammatory efficacy(吲哚美辛衍生物的超分子纳米纤维具有高度的环氧合酶-2(COX-2)选择性并具有抗炎作用)；

药学部陈连国(共一)在高质量T3(B)期刊European Journal of Medicinal Chemistry发表Synthesis and structure-activity relationships of N - (3 - (1H-imidazol-2-yl) phenyl) - 3-phenylpropionamide derivatives as a novel class of covalent inhibitors of p97/VCP ATPase(新型p97/VCP ATP酶共价抑制剂N - (3 - (1H -咪唑-2-基)苯基)- 3-苯基丙酸酰胺衍生物的合成及构效关系)；

转化医学实验室李圆凤(共一)在高质量T3(B)期刊Bioact Mater发表MAVS deSUMOylation by SENP1 inhibits its aggregation and antagonizes IRF3 activation(维持在纳米颗粒和平面上支撑的细胞膜涂层的侧面性和流动性)；

病理科阮静(共一)在高质量T3(B)期刊Clin Transl Med发表OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6(通过非经典方式稳定 CCN6 抑制乳腺癌)；

转化医学实验室李圆凤(共一)在高质量T3(B)期刊Bioact Mater发表Maintaining sidedness and fluidity in cell membrane coatings supported on nano-particlulate and planar surfaces(维持在纳米颗粒和平面上支撑的细胞膜涂层的侧面性和流动性)；